For the first time, human embryonic stem cells have been cultured under chemically controlled conditions without the use of animal substances, which is essential for future clinical uses.
The method has been developed by researchers at Karolinska Institutet and is presented in the journal Nature Biotechnology.
A research team at Karolinska Institutet has now managed to produce human stem cells entirely without the use of other cells or substances from animals. Instead they are cultured on a matrix of a single human protein: laminin-511.
“Now, for the first time, we can produce large quantities of human embryonic stem cells in an environment that is completely chemically defined,” says professor Karl Tryggvason, who led the study.
“This opens up new opportunities for developing different types of cell which can then be tested for the treatment of disease.”
Scientists have performed acupuncture on mice with sore paws to pinpoint how the ancient Chinese medical practice might alleviate pain in humans.
After a half-hour session, the mice felt less discomfort in their paws because the needles triggered the release of a natural painkiller, say the researchers. The needles stimulated cells to produce adenosine, an anti-inflammatory and painkilling chemical, that was effective for up to an hour after the therapy was over.
The discovery challenges a widely held view among scientists that any benefit patients feel after having acupuncture is purely due to the placebo effect.
“The view that acupuncture does not have much benefit beyond the placebo effect has really hampered research into the technique,” said Maiken Nedergaard, a neuroscientist at the University of Rochester Medical Centre in New York, who led the study.
“Some people think any work in this area is junk research, but I think that’s wrong. I was really surprised at the arrogance of some of my colleagues. We can benefit from what has been learned over many thousands of years,” Nedergaard told the Guardian.
Acupuncture was developed in China around 4,000 years ago. The procedure involves inserting fine needles at specific points around the body and then heating, twisting or even electrifying them.
A Houston, Texas man freed last year after spending 23 years in prison for a rape he did not commit cleared another hurdle this week in his quest to be declared “actually innocent.”
DNA test results released in court Tuesday show that Ernest Sonnier, 47, was not involved in a second rape, which ended in a murder for which he was a suspect in 1985, said Alba Morales, the Innocence Project staff attorney handling the case. She said the test excluded Sonnier from being involved.
In the rape for which he was convicted, DNA testing over the past two years implicated two convicted felons as the perpetrators of the 1985 crime.
Scientists have discovered the “Methuselah” genes whose lucky carriers have a much improved chance of living to 100 even if they indulge in an unhealthy lifestyle.
The genes appear to protect people against the effects of smoking and bad diet and can also delay the onset of age-related illnesses such as cancer and heart disease by up to three decades.
No single gene is a guaranteed fountain of youth. Instead, the secret of longevity probably lies in having the right “suite” of genes, according to new studies of centenarians and their families. Such combinations are extremely rare — only one person in 10,000 reaches the age of 100.
The genes found so far each appear to give a little extra protection against the diseases of old age. Centenarians appear to have a high chance of having several such genes embedded in their DNA.
A TV communications satellite is drifting out of control thousands of miles above the Earth, threatening to wander into another satellite’s orbit and interfere with cable programming across the United States, the satellites’ owners said Tuesday.
Communications company Intelsat said it lost control of the Galaxy 15 satellite on April 8, possibly because the satellite’s systems were knocked out by a solar storm. Intelsat cannot remotely steer the satellite to remain in its orbit, so Galaxy 15 is creeping toward the adjacent path of another TV communications satellite that serves U.S. cable companies.
Galaxy 15 continues to receive and transmit satellite signals, and they will probably overlap and interfere with signals from the second satellite, known as AMC 11, if Galaxy 15 drifts into its orbit as expected around May 23, according to the two satellite companies.
AMC 11 receives digital programming from cable television channels and transmits it to all U.S. cable networks from its orbit 22,000 miles above the equator…
A expert would not name any of the cable television channels or providers that could be affected or say how long the interference could last… I assume they have no ideal based on this report, and we will know in coming days.